Fig 1. XRP44X inhibits tumour growth and metastasis in nude mice.

Cells were injected subcutaneously into nude mice, and after 6 days the mice were treated daily by intraperitoneal injection of XRP44X (1 mg/kg). (A) Tumour volume. One representative result is shown, and similar inhibition was observed in four other mice for each condition and cell line. Comparable results were obtained in three separate experiments. (B) Tumour weight after sacrifice. The average weight and standard deviation for 5 mice per condition is shown (p<0.05). (C) Lung metastases. The lungs were excised after sacrifice, photographed and visible metastases were counted. The averages and standard deviations for 5 lungs per condition are shown.