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. 2016 Jul 18;11(7):e0159666. doi: 10.1371/journal.pone.0159666

Fig 2. 17β-estradiol (E2) combined with anti-AGE treatment pyridoxamine (Pyr) increases ER and decreases TGF mRNA in glomeruli of aged ovariectomized female mice.

Fig 2

21 month-old ovariectomized female C57/B6 mice were treated with either placebo (pla), 17-estradiol (E2), pyridoxamine (Pyr) or E2+ Pyr for 2 months. Real time-PCR for ER and TGF were performed as described in methods. Data are graphed as mean ± SEM.*p <0.05 compared to pla, ***p<0.005 compared to pla, # p<0.05 compared to pla. n = 5–7 mice/group.