Table 1. Effect of pyridoxamine and 17β-estradiol replacement on body, kidney, uterine weight and albumin/creatinine ratio.
Pla (n = 10) | E2 (n = 12) | Pyr (n = 10) | Pyr+E2 (n = 6) | |
---|---|---|---|---|
Body weight (g) | 31 ±1.3 | 30±0.9 | 31±1.5 | 30±1.4 |
Kidney weight (g) | 0.28±0.01 | 0.29±0.01 | 0.27±0.009 | 0.34±0.2 a |
Uterine weight (g) | 0.02±0.00b | 0.14±0.02c | 0.02±0.001d | 0.15±0.02 |
Albumin/Creatinine ratio | 0.43±0.32 | 0.26±0.06 | 0.34±0.06 | 0.25±0.05 |
a *p<0.05 compared to placebo (pla) and pyridoxamine (Pyr)
b***p<0.005 compared to 17β-estradiol (E2) and Pyr+E2
c***p<0.005 compared to Pyr
d ***p<0.005 compared to Pyr+E2.