Table 3.
Comparison of the most commonly observed sequence types (STs) and associated serotypes of Streptococcus pneumoniae in the PCV7 vs. PCV13 eras
| Common Sequence types | # (%) of Spn MLST typed in PCV7 period (n=289) | # (%) of Spn MLST typed in PCV13 period (n=503) | Main Serotypes associated with ST |
|---|---|---|---|
| 199 | 29 (10.0%) | 42 (8.3%) | 19A, 15B, 15A, 15C |
| 558† | 12 (4.2%) | 66 (13.1%)† | 35B, 35 (not B) |
| 62 | 19 (6.6%) | 44 (8.8%) | 11A, 11B, 11C, 6A, 35, 9 |
| 432 | 7 (2.4%) | 32 (6.4%) | 21 |
| 439 | 6 (2.1%) | 23 (4.6%) | 23A, 23B |
| 320† | 21 (7.3%) | 5 (1.0%) | 19A |
| 338 | 8 (2.8%) | 20 (4.0%) | 23A, 23B, 21 |
| 433 | 13 (4.5%) | 16 (3.2%) | 2211C |
| 1262 | 6 (2.1%) | 13 (2.6%) | 15A, 15B, 15C |
| 816 | 5 (1.7%) | 7 (1.4%) | 10, 39 |
| 695 | 7 (2.4%) | 6 (1.2%) | 19A |
| 1847 | 10 (3.5%) | 2 (0.4%) | 23B, 23A |
| 63 | 5 (1.7%) | 6 (1.2%) | 15A |
| 2733 | 3 (1.0%) | 8 (1.6%) | 19A |
| 473 | 3 (1.0%) | 6 (1.2%) | 6A, 6C, 21 |
| 1292 | 5 (1.7%) | 3 (0.6%) | 6A, 6C, 11C, 21 |
| 7927 | 4 (1.4%) | 4 (0.8%) | 21, 12 |
| 448* | 0 | 7 (1.4%) | NT |
| 498 | 2 (0.7%) | 9 (1.8%) | 35 (not B) |
| 36* | 0 | 5 (1.0%) | 23B |
| 1379 | 5 (1.7%) | 1 (0.2%) | 6A, 6C |
| 3280* | 0 | 5 (1.0%) | 35B, 15B, 15C |
| 1840* | 0 | 6(1.2%) | 23B, 15B |
| 235* | 0 | 5(1.0%) | 20 |
| 3811* | 0 | 13(2.5%) | 15A |
Note
*
represent STs only observed in PCV13 period.
†
represent significant difference (p<0.0001) between PCV7 and PCV13.