Figure 1.
(A) Effect of various magnitudes of TENS on IL-1β-dependent PGE2 production. PDL cells were incubated with IL-1β (1 ng/mL) and simultaneously exposed to 0%, 3%, 6%, 10%, or 12.5% TENS for 24 h. (B) Effect of TENS on PGE2 production in response to various concentrations of rhIL-1β. PDL cells were treated with 0, 0.1, 0.5, 1, 5, 10, or 25 ng/mL of rhIL-1β for 24 h with or without simultaneous exposure to 6% TENS for 24 h. PGE2 accumulation in the culture supernatants was assessed by radioimmunoassay. Data represent mean and SEM of triplicate values in all experiments. *p ≤ 0.05 vs. cells treated with rhIL-1β alone; ✠p < 0.05 vs. untreated control cells.
