Fig. 2.

Patients with Candida esophagitis have decreased peripheral natural killer cell counts and innate lymphoid cells.

(a) Absolute CD3⁻CD56⁺ natural killer cell counts, percentage of CD16⁺ natural killer cell counts and absolute CD16⁺CD3⁻CD56⁺ natural killer cell counts, (b) percentages of NKG2A⁺ and NKG2C⁺ natural killer cell counts, (c) percentage of proliferating (CFSE^dim) cells in the natural killer cell population after 7 days stimulation with staphylococcal enterotoxin B or heat-inactivated C. albicans and (d) absolute lineage⁻CD127⁺ innate lymphoid cell-count of patients at diagnosis of Candida esophagitis (ESO), patients with early initiated combination antiretroviral therapy and a viral load less than 50 copies/ml (viral load <50) and healthy donors. Shown are median values + interquartile ranges (Tukey plot). Data in (b) are shown after subtraction of unstimulated controls. Number of ESO/viral load less than 50/healthy donor were n = 31/15/20 (a, b and d) and n = 4/8/14 (c). ^∗∗P ≤ 0.01, ^∗∗∗P ≤ 0.001 and ^∗∗∗∗P ≤ 0.0001 (Mann–Whitney test).