Skip to main content
. 2016 Apr 7;157(8):1761–1772. doi: 10.1097/j.pain.0000000000000579

Figure 5.

Figure 5.

(A) Restrained animals showed decreased behavioral responses (weighted pain scores) to 1% formalin injection in the hind paw compared with control animals, when tested 2 weeks after restraint (F(1,264) = 17.69, P < 0.0001). *P < 0.05, **P < 0.01, controls vs restrained groups. n = 11 to 12 per group. (B) Both restrained and control animals showed increases in CORT responses vs baseline after the formalin test (REST P = 0.003, CON P = 0.02, 1-tailed Wilcoxon matched-pairs signed rank test). *P < 0.05 and **P < 0.01 post-restraint vs baseline, n = 11 to 12 per group. BL, baseline; CORT, corticosterone; Post, post formalin.