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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Crit Care Med. 2016 Aug;44(8):e639–e650. doi: 10.1097/CCM.0000000000001629

Fig.1. Down-regulation of miR-126a-3p in endotoxic mouse arteries, in vascular ECs isolated from endotoxic aortas and lungs, and in septic human vessels.

Fig.1

A. miR-126a-3p levels in endotoxic mouse aortas at 6 hours after LPS injection (20 mg/kg, ip) (n=8) and in control aortas isolated from vehicle-treated mice (n=8) (500 μl, ip) determined by qRT-PCR. Note: *p<0.05 compared with that in control aortas. B. miR-126a-3p levels in vascular ECs isolated from endotoxic mouse aortas (macro-vascular ECs) (n=6) and from normal control mouse aortas (n=6) determined by qRT-PCR. Note: *p<0.05 compared with that in ECs from control aortas. C. miR-126a-3p levels in vascular ECs isolated from endotoxic lungs (micro-vascular ECs) (n=6) and from normal control mouse lungs (n=6) determined by qRT-PCR. Note: *p<0.05 compared with that in ECs from control lungs. D. miR-126a-3p levels in vessels of skin biopsy samples from patients with sepsis (n=5) and from control subjects (n=5) determined by qRT-PCR. Note: *p<0.05 compared with that in vessels from control subjects.