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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Crit Care Med. 2016 Aug;44(8):e651–e663. doi: 10.1097/CCM.0000000000001637

Figure 4.

Figure 4

SRT1720 inhibits liver neutrophil infiltration after hepatic ischemia-reperfusion (I/R). Ischemic liver tissues of the vehicle- and SRT1720-treated mice were collected at 24 h after reperfusion. The mRNA levels of (A) keratinocyte-derived chemoattractant (KC) and (B) macrophage inhibitory protein-2 (MIP-2) were measured by RT-PCR. (C) Myeloperoxidase (MPO) activity was determined spectrophotometrically. (D) Immunohistochemistry staining of neutrophils using anti-granulocyte receptor 1 (anti-Gr-1) antibody. Data are presented as means ± SE (n = 6-8/group). *P < 0.05 versus control; #P < 0.05 versus vehicle.