Table 1. Summary of physiologic variables in WT mice used for experiments on brain water content at 24 hr following CA/CPR.

	NS Surgical Shams	NS CA/CPR	3% HS Surgical Shams	3% HS CA/CPR	5% HS Surgical Shams	5% HS CA/CPR	7.5% HS Surgical Shams	7.5% HS CA/CPR
N	8	15	8	13	7	12	9	13
Body weight (g)	24.5±0.4	24.1±0.6	24.2±0.5	24.9±0.4	24.5±0.5	24.7±0.4	24.7±0.5	24.3±0.4
CPR duration (sec)		61±6		60±5		60±7		61±8
Epinephrine (μg)		8.8±0.2		8.7±0.2		8.8±0.2		8.9±0.2
Survival rate (%)	100%	80%	100%	85%	100%	83%	100%	77%
Sodium (mmol/L) at end of experiment	145±1	146±1	147±1	147±1	152±1*	152±1*	155±2*	156±3*
Osmolality (mOsm/L) at end of experiment	317±2	314±1	317±1	318±2	325±2¶	326±2¶	347±9¶	345±5¶
Neuroscore		7 (4.5–8)		7 (4–9)		6 (3–9)		4 (3–4.5)*

Neuroscore is presented as median with 25 and 75% quartiles. All other data indicates mean ± standard error of the mean (SEM); CA/CPR, cardiac arrest and cardiopulmonary resuscitation; NS, 0.9% saline; HS, hypertonic saline

^*P < 0.05 vs. NS and 3% treatment groups;

^¶P < 0.05 vs. all other treatment groups