Table 2. Physiologic variables in α-Syn-/- mice used for experiments on brain water content at 24 hr following CA/CPR.
NS Surgical Shams | NS CA/CPR | 7.5% HS Surgical Shams | 7.5% HS CA/CPR | |
---|---|---|---|---|
N | 6 | 12 | 6 | 14 |
Body weight (g) | 24.5±0.4 | 24.1±0.6 | 24.7±0.5 | 24.3±0.4 |
CPR duration (sec) | 65±5 | 64±6 | ||
Epinephrine (μg) | 8.9±0.2 | 9.0±0.2 | ||
Survival rate (%) | 100% | 75% | 100% | 71% |
Sodium (mmol/L) at end of experiment | 145±1 | 146±1 | 152±2* | 157±4* |
Osmolality (mOsm/L) at end of experiment | 316±3 | 316±4 | 340±5* | 351±7* |
Neuroscore | 7 (7–9) | 8 (5.5–8.5) |
Neuroscore is presented as median with 25 and 75% quartiles.
All other data indicates mean ± standard error of the mean (SEM).
CA/CPR, cardiac arrest and cardiopulmonary resuscitation; NS, 0.9% saline;
HS, hypertonic saline.
P < 0.05 vs. NS treatment groups