Table 1.
Clinical and demographic variables according to injured area (cortical and subcortical) and presence or absence of motor evoked potential (MEP) at baseline assessment.
Injury location | Motor evoked potential | |||||
---|---|---|---|---|---|---|
Cortical | Subcortical | p | Present | Absent | p | |
N | 23 | 33 | – | 29 | 27 | – |
Age (years)* | 8.1 (1.7) | 7.5 (1.9) | 0.48 | 8.0 (2.0) | 7.8 (2.1) | 0.71 |
Active tDCS | 7.3 (1.6) | 7.1 (1.1) | 0.23 | 7.6 (1.6) | 7.9 (1.9) | 0.75 |
Sham tDCS | 7.5 (1.8) | 7.8 (1.1) | 0.76 | 8.1 (1.3) | 7.6 (2.2) | 0.81 |
GMFCS (I/II/III)** | 1/10/12 | 4/13/16 | 0.51 | 3/14/12 | 2/9/16 | 0.46 |
Active tDCS | 0/5/5 | 3/10/10 | 0.48 | 1//10/8 | 1/4/9 | 0.47 |
Sham tDCS | 1/5/7 | 1/3/6 | 0.91 | 2/4/4 | 1/5/7 | 0.94 |
Hemiparetic/Diparetic** | 2/21 | 3/30 | 0.92 | 4/25 | 1/26 | 0.80 |
Active tDCS | 1/9 | 2/21 | 0.40 | 3/16 | 1/13 | 0.41 |
Sham tDCS | 1/12 | 1/9 | 0.84 | 1/9 | 0/13 | 0.37 |
6MWT (m)* | 252.4 (62.7) | 241.4 (70.2) | 0.54 | 261.3 (98.4) | 249.9 (80.2) | 0.45 |
Active tDCS | 242.3 (25.1) | 250.5 (57.8) | 0.98 | 261.2 (20.6) | 242.3 (25.1) | 0.30 |
Sham tDCS | 227.9 (40.8) | 251.0 (49.9) | 0.06 | 249.4 (43.3) | 227.7 (40.8) | 0.25 |
Gait speed (m/s)* | 0.58 (0.17) | 0.55 (0.12) | 1.0 | 0.61 (0.13) | 0.54 (0.12) | 0.04 |
Active tDCS | 0.54 (0.07) | 0.57 (0.05) | 0.53 | 0.55 (0.06) | 0.54 (0.007) | 0.05 |
Sham tDCS | 0.51 (0.16) | 0.48 (0.11) | 0.03 | 0.48 (0.07) | 0.48 (0.06) | 0.08 |
Gait profile score (°)* | 11.3 (2.1) | 12.1 (2.9) | 0.23 | 11.9 (3.1) | 11.2 (1.7) | 0.30 |
Active tDCS | 11.8 (0.6) | 11.5 (1.0) | 0.06 | 11.2 (0.5) | 11.2 (0.6) | 0.28 |
Sham tDCS | 11.3 (0.6) | 11.3 (1.0) | 0.61 | 10.9 (0.6) | 10.9 (0.7) | 0.33 |
MEP (mV)* | 1.5 (0.5) | 1.6 (0.4) | 0.42 | 1.6 (0.7) | – | – |
Active tDCS | 0.9 (0.6) | 0.8 (0.7) | 0.78 | 1.3 (0.2) | – | – |
Sham tDCS | 0.7 (0.4) | 0.7 (0.6) | 0.93 | 1.2 (0.3) | – | – |
Active tDCS (%) | 10 (43.7%) | 23 (69.6%) | 19 (65.5%) | 14 (51.8%) |
Legend: GMFCS, gross motor function classification system; tDCS, transcranial direct current stimulation; 6MWT (m), six-minute walk test; MEP, motor evoked potential. *Data expressed as mean and standard deviation. Analyses performed with unpaired t-test. **Numbers indicate frequency (n) of children in each group. Analyses performed with Chi-square.