1.
Biodistribution of 111In-labeled trastuzumab-based agents in SKBR-3 tumor-bearing nude mice at 48 h after injection
| Tissue | Biodistribution (x±s, %ID/g) | |||
| m=0 | m=2 | m=3 | m=5 | |
| Blood | 0.93±0.33 | 0.78±0.27 | 0.92±0.28 | 1.00±0.18 |
| Liver | 8.33±4.09 | 7.41±1.24 | 8.09±1.39 | 8.84±1.97 |
| Kidney | 5.43±2.42 | 15.63±1.28 | 25.99±1.52 | 28.37±4.55 |
| Muscle | 0.98±0.54 | 0.81±0.33 | 1.18±0.14 | 1.27±0.35 |
| Bone | 2.92±0.39 | 0.91±0.51 | 6.54±2.52 | 6.02±1.26 |
| Tumor | 15.76±2.61 | 9.96±1.05 | 8.84±1.85 | 6.77±1.73 |