Table 3. Effect of a 14-day IP saline and insulin and subcutaneous metformin treatment on body weight gain, and plasma glucose and triglycerides levels and somatic index.

	Body weight gain (g)	Glucose (mg/dl)	Triglycerides (mg/dl)	Somatic index. Liver (g/100 g BW)	Somatic index. Epididymal (g/100 g BW)	Somatic index. Visceral (g/100 g BW)
Control	50.0 ± 1.8 a	131.8 ± 4.7 a	116.6 ± 6.5 a	3.5 ± 0.1 a	1.57 ± 0.09 a	1.0 ± 0.06
Metformin	20.7 ± 7.4 b	91.0 ± 11.5 b	97.5 ± 10.5 a,b	3.3 ± 0.2 a,b	1.20 ± 0.03 b	0.9 ± 0.06
Insulin	41.4 ± 1.6 c	70.5 ± 10.5 b	69.76 ± 4.84 b	3.0 ± 0.1 b	1.63 ± 0.12 a	1.0 ± 0.04

Values are expressed as mean   SEM. Different letters indicate statistical differences by treatment (One-way ANOVA with post hoc Tukey test, a value of P < 0.05 was considered statistically significant). N = 6 (metformin treatment) or 8 (saline and insulin treatments). Somatic index was calculated as the ratio between tissues weight and body weight and was expressed as g/100 g body weight (BW).