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. 2016 Jul 19;6:29789. doi: 10.1038/srep29789

Figure 5. Protective action of VCE-003.2 administration in QA-induced excitotoxicity in vivo.

Figure 5

(a) CD1 mice were subjected to quinolinic acid (QA) intrastriatal injection and RotaRod performance (fold change) was determined 2 days after lesion in vehicle- and VCE-003.2-treated mice (10 mg/kg). (b) Representative MRI images (Upper panel) and edema volume quantification (lower panel) 5 days after QA injection. Values are expressed as means ± SEM. Sham-Veh and Sham-VCE (n = 7 in each group); QA-Veh (n = 8); QA-VCE (n = 7). **p < 0.01, ***p < 0.001 vs. Vehicle. #p < 0.05 vs. QA.