Figure 4.

Effect of repeated mustard oil application to the snout (• first application; ∘ second application) on heel–medial gastrocnemius (MG), toes–tibialis anterior (TA) and toes–semitendinosus (ST) reflexes in the absence (top panels) or presence (bottom panels) of RX 821002 (100–300 μg, intrathecally) prior to the second injection. Each point on the graphs represents the median of nine (no drug group) or 10 (RX 821002 group) experiments, and the vertical lines are either 1st or 3rd quartiles. Mustard oil was applied at 0 min. *Indicates a significant difference in the effect of mustard oil at equivalent time points before and after intrathecal RX 821002 (Wilcoxon tests, P < 0.05).