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. 2016 Mar 10;11(12):1380–1394. doi: 10.1002/cmdc.201500592

Figure 3.

Figure 3

Evaluation of compounds used for IC50 measurements. In a first set of experiments, the effect of all compounds at 100 μm final concentration was tested on P‐gp (dark grey bars) and BCRP (light grey bars) using intracellular accumulation assay as described in the Experimental Section. Data are shown as % inhibition compared with the positive control verapamil (P‐gp) or Ko143 (BCRP) and are given as mean±SD of a single experiment with at least duplicate measurements.