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. Author manuscript; available in PMC: 2016 Jul 19.
Published in final edited form as: Cancer Res. 2011 Aug 18;71(20):6535–6546. doi: 10.1158/0008-5472.CAN-11-0329

Figure 1. Kiss1r heterozygosity affects mammary tumor latency, multiplicity, growth and lung metastasis.

Figure 1

(A) Kaplan-Meier plot for palpable tumors until 16 weeks. (B) Breast tumor numbers in different mammary fat pads between PyMT-Kiss1r wild type (Kiss1r+/+) and PyMT-Kiss1r+/− (Kiss1r+/−). (C) The volume of primary tumors in 11 week-old mice. (D) Metastatic tumor foci number in lung tissues at 11 weeks of age in wild-type (Kiss1r+/+) and heterozygosity mice (Kiss1r+/−).