Skip to main content
. Author manuscript; available in PMC: 2016 Jul 19.
Published in final edited form as: Cancer Res. 2011 Aug 18;71(20):6535–6546. doi: 10.1158/0008-5472.CAN-11-0329

Figure 2. Kiss1r heterozygosity attenuates the incidence of mammary hyperplasia, solid tumor formation and tumor malignance.

Figure 2

(A) Primary tumor development in 4th inguinal mammary fat pad from 5 to 9 weeks of age. Arrows indicate primary tumors. (B) Hyperplastic nodules (the inbox) at 5 weeks of age. Inbox represents the hyperplastic nodule image. (C) Tumor malignancy in PyMT/Kiss1r+/+ (wild type) and PyMT/Kiss1r+/− (heterozygous mice). (D) Immunohistochemistry for Kiss1r in tumor tissues.