Fig. 2.

(A) Epifluorescence microscopy of planktonic E. coli (−) after incubation with PSVue-380 (10 μM). (B) Saliva sample containing human epithelial cells (stained red) with an associated ‘clump’ of bacteria stained with PSVue-380 (blue). A and B reproduced with permission from Ref. 113 © Royal Society of Chemistry. (C) Fluorescence microscopy image of human A-549 cells and E. coli K12 (−) cell mixtures were stained with DAPI (1 μg/mL), and treated 15 min later with tetra-ZnDPA-SR. (D) Optical image of a mouse with a S. aureus infection in the left rear leg at 21 hours after intravenous injection of PSVue-794. Reprinted with permission from Ref. 116. © 2006 American Chemical Society. (E) Whole-body fluorescence and bioluminescence imaging of an athymic mouse containing a leg infection of bioluminescent S. enterica serovar typhimurium FL6 (−) and imaged 3 hours after dosage with tetra-ZnDPA-SR. Reprinted with permission from Ref. 119. © 2010 American Chemical Society. (F) SPECT/CT image of a mouse with a leg infection of S. pyogenes and imaged 20 hours post-administration of bis-ZnDPA-[¹¹¹In]DTPA. Reproduced from with permission Ref. 125. © 2015 Springer.