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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Am J Surg Pathol. 2016 Aug;40(8):1125–1132. doi: 10.1097/PAS.0000000000000656

TABLE 2.

Categorization of RP Cases Misclassified Preoperatively as Having Insignificant PCa

Category 1 Category 2 Category 3 Category 4
GS 3+3 = 6 (GG 1), DTNV > 0.5 cm3, and OC or fEPE GS 3+4 = 7 (GG 2) and OC GS 3+4 = 7 (GG 2) with nfEPE GS > 4+3 = 7 (GG 3)

The definitions of misclassification categories are adopted from a prior PCa expert survey.6 Only misclassifications encountered in this study are included in the table. Tumor nodules with dominant Gleason pattern 3 and patter 4 <5% are classified as Gleason score 3+4 = 7 (GG 2) according to the 2014 International Society of Urologic Pathology recommendation.8

DTNV indicates dominant tumor nodule volume; fEPE, focal extraprostatic extension; GS, Gleason score; nfEPE, nonfocal extraprostatic extension; OC, organ confined.