Table 1.
Principal connections of the pedunculopontine tegmental nucleus; representative references are given for each cluster
| Midbrain, brain stem, cerebellum, and spinal cord | |
| Inferior and superior colliculus (reciprocal) | 96, 97, 98 |
| Pontine and medial reticular formation; nucleus pontis oralis | 99, 100, 101, 102 |
| Motor trigeminal | 103, 104, 105 |
| Medulla | 99, 106 |
| Spinal cord (reciprocal) | 107, 108, 109 |
| Ascending reticular activating system | |
| Dorsal raphe, locus coeruleus, laterodorsal tegmental nucleus | 70, 107, 110, 111 |
| Forebrain | |
| Thalamus | 112, 113, 114, 125 |
| Basal ganglia—striatum; globus pallidus (internal and external); subthalamic nucleus; substantia nigra pars reticulata; and projections to midbrain dopamine‐containing neurons | 47, 107, 115, 116, 117, 118, 119, 120 |
| Extended amygdala, basal forebrain, lateral hypothalamus | 113, 118, 121, 122 |