Table 3.

Risk of hip/femur fracture associated with current use of BZD from SCCS studies in BIFAP and CPRD including adjustment for event‐exposure dependence

	BIFAP (N = 4450)								CPRD (N = 8333)
			Model crude			Model adjusted by age					Model crude			Model adjusted by age
	Cases	Follow‐up days	IRR	IC (95%)		IRR	IC (95%)		Cases	Follow‐up days	IRR	IC (95%)		IRR	IC (95%)
Past/non‐use	1898	4 941 912	1.00	—	—	1.00	—	—	5549	15 344 912	1	—	—	1	—	—
Recent use	172	361 218	1.37	1.16	1.60	1.21	1.03	1.42	401	712 289	1.58	1.43	1.76	1.41	1.27	1.57
Current use	1543	2 945 532	1.77	1.62	1.93	1.43	1.31	1.57	1834	3 274 091	1.75	1.63	1.87	1.37	1.27	1.47
1–30 days	213	409 985	1.58	1.36	1.83	1.40	1.21	1.62	342	510 624	1.79	1.60	2.00	1.59	1.42	1.78
31–60 days	201	362 943	1.69	1.45	1.97	1.49	1.28	1.74	253	425 445	1.62	1.43	1.85	1.42	1.25	1.62
61–182 days	314	614 880	1.63	1.43	1.86	1.37	1.20	1.57	383	647 956	1.68	1.50	1.89	1.35	1.20	1.51
183–365 days	246	437 601	1.95	1.68	2.27	1.53	1.32	1.79	300	498 354	1.88	1.65	2.14	1.36	1.19	1.55
>365 days	569	1 120 123	2.27	1.97	2.60	1.42	1.22	1.65	556	1 191 712	1.83	1.62	2.06	1.02	0.90	1.16
Pre‐exposure period	837	343 657	7.17	6.55	7.84	6.47	5.91	7.09	549	505,200	2.83	2.59	3.11	2.52	2.30	2.76