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. 2015 Jul 27;230(11):2796–2806. doi: 10.1002/jcp.25006

Figure 3.

Figure 3

Immunohistochemical localization of IGF‐2 and IGFBP3 to the proliferating and hypertrophic chondrocytes of WT and Socs2‐/‐ growth plates. In contrast to WT growth plates, hypertrophic chondrocytes within the Socs2‐/‐ growth plate expressed high levels of both IGF‐2 and IGFBP3 (arrows). Scale bars = 50μm