Fig. 1. Cystometrograms with intravesical infusion of saline at 150 µL per minute in conscious rats. Voiding bladder contractions, micturition frequency and voided volumes are shown at 8- and 16-week bladder ischemia versus sham controls. Changes in intravesical pressure and micturition patterns consistent with bladder overactivity and changes resembling detrusor underactivity were evident in the 8- and 16-week ischemic bladders, respectively.
