Table 1.

Effect of FXM and its fractions in acetic acid induced writhing test in rat

Groups	Drug (dose), route	No. of writhing (Mean ± SD)	% Inhibition
Saline	2 ml, i.p.	71.00 ± 2.52a	0
FXM	100 mg/kg, p.o.	30.50 ± 1.87g	57.04 ± 3.63
FXM	200 mg/kg, p.o.	22.00 ± 3.41h	69.01 ± 4.98
FXH	100 mg/kg, p.o.	63.50 ± 1.87b	10.56 ± 2.63
FXH	200 mg/kg, p.o.	51.00 ± 2.19de	28.16 ± 3.08
FXC	100 mg/kg, p.o.	39.16 ± 3.48f	44.83 ± 4.91
FXC	200 mg/kg, p.o.	16.16 ± 3.62ij	77.23 ± 5.64
FXE	100 mg/kg, p.o.	59.00 ± 1.41bc	16.90 ± 2.02
FXE	200 mg/kg, p.o.	48.00 ± 2.44e	32.39 ± 3.14
FXB	100 mg/kg, p.o.	55.66 ± 1.63cd	21.59 ± 2.30
FXB	200 mg/kg, p.o.	52.16 ± 1.16de	26.52 ± 1.64
FXA	100 mg/kg, p.o.	62.00 ± 1.78b	12.67 ± 2.51
FXA	200 mg/kg, p.o.	54.33 ± 1.75cd	23.47 ± 2.46
Diclofenac sodium	10 mg/kg, i.p.	14.16 ± 2.60j	80.04 ± 5.25
Aspirin	10 mg/kg, i.p.	19.16 ± 2.46hi	73.00 ± 4.87

FXM F. xanthoxyloides methanol extract, FXH F. xanthoxyloides n-hexanefraction, FXC F. xanthoxyloides chloroform fraction, FXE F. xanthoxyloides ethyl acetate fraction, FXB F. xanthoxyloides n-butanol fraction, FXA F. xanthoxyloides residual aqueous fraction. Data values shown represent mean ± SD (n = 6). One-way ANOVA followed by Tukey’s HSD multiple comparison tests. Different alphabets in each column indicate difference at P <0.05