Table 1.

In vivo studies reporting treatment failure with sulfadoxine-pyrimethamine (SP) as monotherapy and in combination with other anti-malarial drugs.

Author	Location	State	Year	SP	SP +CQ	SP +AQ	SP +AS	Reference
Adam 2004	New Halfa	Kassala	1999	0	ND	ND	ND	18
Adam 2004a	New Halfa	Kassala	2001	16.7	ND	ND	ND	28
Stivanello 2004	Mundri, Kajo Keji county	Western Equatoria	2001	69.1	ND	ND	ND	20
Van den broek 2003	Lankien	Upper Nile	2001	0	ND	ND	ND	19
A-Elbasit 2006	Darawish, Kajara	Gedaref	2003	31.7	36.6	ND	ND	29
Salah 2005	Kassala Town	Kassala	2003	15	2.5	ND	ND	30
Elamin 2007	Obeid	Northern Kordofan	2003	4.2	ND	ND	ND	17
Elamin 2007	Medani	Gezira	2003	2	ND	ND	ND	17
Elamin 2007	Kassala (Kassala state)	Kassala	2003	7.7	ND	ND	ND	17
Elamin 2007	Khartoum	Khartoum	2003	ND	14.5	ND	ND	17
Elamin 2007	Damazin	Blue Nile	2003	4	5.9	ND	ND	17
Hamour 2005	Limun village	Southern Kordofan	2003	ND	ND	7.2	8.8	33
Adam 2005	New Halfa	Kassala	2004	13.3	ND	ND	0	31
Mohamed 2006	Kosti	White Nile	2004	ND	ND	ND	0	36
Elamin 2005	Damazin	Blue Nile	2004	ND	ND	ND	0	37
Elamin 2005	Kassala Town	Kassala	2004	ND	ND	ND	4	37
Elamin 2005	Kosti	White Nile	2004	ND	ND	ND	0	37
Elamin 2005	Malakal	Upper Nile	2004	ND	ND	ND	0	37
Van Den Broek 2005	Malakal	Upper Nile	2003–4	ND	ND	1	0.9	39
Ibrahium 2007	New Halfa	Kassala	2005	ND	ND	4.8	2.5	32
Mukthar 2007	Asar, Abunaja Juama, Abunaja Bargo	Gedaref	2004–5	ND	ND	ND	15.6 (6.5)	38

AQ – amodiaquine, AS – artesunate, CQ -chloroquin ND – not done, SP – sulfadoxine-pyrimethamine.