Table 4.
Effect of tomato and broccoli extract on serum resistin, leptin and adiponectin in HFD induced obesity in rats
| Groups | Resistin (ng/ml) | Leptin (Pg/ml) | Adiponectin (Pg/ml) |
|---|---|---|---|
| Control | 0.93 ± 0.05 | 16.3 ± 0.57 | 120 ± 3.81 |
| HFD | 11.2 ± 0.48* | 147 ± 3.70* | 27.8 ± 0.94* |
| SD | 8.05 ± 0.29*,** | 118 ± 4.20*,** | 40.2 ± 2.36*,** |
| T 200 | 4.13 ± 0.22*,**,*** | 44.8 ± 2.13*,**,*** | 95.5 ± 3.84*,**,*** |
| T 400 | 1.51 ± 0.04*,**,*** | 22.7 ± 0.84*,**,*** | 131 ± 3.84*,** |
| B 200 | 5.91 ± 0.29*,**,*** | 80.3 ± 3.14*,**,*** | 78.5 ± 2.42*,**,*** |
| B 400 | 2.32 ± 0.15*,**,***,**** | 41 ± 2.45*,**,***,**** | 122 ± 3.61*,** |
| CX | 1.37 ± 0.03*,**,***,**** | 45.7 ± 2.91*,**,***,**** | 112 ± 4.77**,***,**** |
Tomato and broccoli extracts treatment at different doses significantly reduced serum resistin and leptin while increased adiponectin levels in HFD rats. C = control; HFD = high fat diet; SD = stop diet; T 200 = tomato extract 200 mg/kg; T 400 = tomato 400 mg/kg; B 200 = broccoli 200 mg/kg; B 400 = broccoli 400 mg/kg; CX = Chromax
*= Significant from control at P < 0.0001, **Significant from HFD at P < 0.0001, ***Significant from SD at P < 0.05, ****Significant from T 400 at P < 0.001. Results were expressed as mean ± SEM and analyzed using one-way ANOVA followed by Bonferroni’s post hoc test