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. Author manuscript; available in PMC: 2016 Jul 19.
Published in final edited form as: J Alzheimers Dis. 2016;52(3):887–898. doi: 10.3233/JAD-150867

Table 4.

Restricted analyses of change in quality of life (QOL) at retirement and later cognitive decline

Decline in global composite scoreab

Selection criteria N Worse Same Improved p-trendd
Subjective memory complaint scorec ≤1 2,473 0.004 (−0.016, 0.024) 0 (Ref) 0.006 (−0.004, 0.015) 0.40
Baseline global composite score > p10 3,887 0.003 (−0.012, 0.018) 0 (Ref) 0.011 (0.003, 0.019)** 0.016
Baseline TICS ≥34 2,966 0.003 (−0.014, 0.020) 0 (Ref) 0.014 (0.005, 0.022)** 0.005
Underwent all 4 interviews 3,537 0.007 (−0.007, 0.022) 0 (Ref) 0.010 (0.002, 0.017)** 0.07
Age at retirement ≥65 1,587 −0.001 (−0.023, 0.021) 0 (Ref) 0.008 (−0.004, 0.021) 0.17
No antidepressant use and SF-36
Vitality score ≥50 and SF-36 Mental Health score >=53
3,906 0.013 (−0.006, 0.031) 0 (Ref) 0.011 (0.003, 0.019)** 0.09
*

p<0.05;

**

p<0.01;

***

p<0.001

a

Global composite score is the average of the z-scores of the TICS, delayed recall of the TICS 10-word list, immediate and delayed recalls of the East Boston Memory Test, category fluency and digit span backward

b

All models are multivariable-adjusted as indicated in footnote c of Table 3

c

Score defined as the number of positive response(s) among seven items: change in memory, difficulties in remembering a short list of items, difficulties in remembering things from one second to the next, difficulties in remembering recent events, difficulties in understanding instructions, difficulties in following a conversation, difficulties in finding the way around familiar streets; in our sample, ‘1’ is the median score

d

Test for linear trend using the ordinal score on categories of QOL change at retirement