Immunohistochemistry staining revealing FOXP3 protein expression in gastric lesion tissues. (A) Nuclear FOXP3 staining in (A) invasive carcinoma, (B) early invasive carcinoma and (C) carcinoma in situ tissues (stain, HE; magnification, ×200). (D) Nuclear FOXP3 staining in early invasive carcinoma (arrow) (stain, HE; magnification, ×100). FOXP3, forkhead box protein 3; HE, hematoxylin and eosin.