Table II.
Comparison of patient clinical backgrounds between the early colectomy group and the non-early colectomy group.
| Clinical characteristic | Early colectomy group | Non-early colectomy group | P-value |
|---|---|---|---|
| No. of patients (M/F) | 12 (8/4) | 73 (44/29) | 0.6737 |
| Age (mean; years) | 35.7 | 34.4 | 0.7181 |
| Disease duration (mean; months) | 37.8 | 61.8 | 0.1770 |
| Seo index (no. of patients <220/≥220) | 2/10 | 43/30 | 0.0066 |
| Disease severity (no. of patients with left-sided colitis/pancolitis) | 2/10 | 27/46 | 0.1689 |
| Disease course (no. of patients with first attack/chronic continuous/relapse remitting ulcerative colitis) | 3/4/5 | 6/19/48 | 0.2127 |
| Previous cytapheresis therapy (no. of patients with/without) | 6/6 | 36/37 | 0.9649 |
| Previous biologics treatment (no. of patients with/without) | 0/12 | 4/69 | 0.4062 |
| Previous AZA or 6-MP treatment (no. of patients with/without) | 1/11 | 28/45 | 0.0421 |
| Hematocrit levels (mean %) | 30.0 | 35.6 | 0.0038 |
| White blood cell count/mm3 (mean) | 9,633 | 9,441 | 0.8797 |
| Lymphocyte count/mm3 (mean) | 930 | 1,231 | 0.1387 |
| Platelet count (mean; ×103/mm3) | 309 | 347 | 0.3979 |
| Albumin levels (mean; g/dl) | 2.95 | 3.41 | 0.0256 |
| C-reactive protein levels (mean; mg/dl) | 930 | 1,231 | 0.1387 |
| O-PNI (mean) | 34.15 | 40.27 | 0.0069 |
| C7-HRP (no. of patients with positive/negative C7-HRP) | 6/6 | 17/56 | 0.0536 |
| PSL≥10,000 mg (no. of patients with/without PSL≥10,000 mg) | 3/9 | 9/64 | 0.2427 |
Left-sided colitis refers to patients who have mucosal lesions restricted to the rectum, sigmoid colon and descending colon. M, male; F, female; AZA, azathioprine; 6-MP, 6-mercaptopurine; O-PNI, onodera-prognostic nutritional index; C7-HRP, cytomegalovirus antigenemia; PSL, prednisolone.