Table IV.
Multivariate analysisa of OS and DMFS.
| OS | DMFS | |||||
|---|---|---|---|---|---|---|
| Parameter | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Model 1-SUVmax | ||||||
| SUVmax (≥28.5/<28.5) | 3.94 | 1.13–12.71 | <0.04 | 2.00 | 0.42–7.35 | 0.34 |
| T category (T4/T1-3) | 5.10 | 1.20–20.52 | <0.03 | 2.40 | 0.55–9.91 | 0.24 |
| Treatment group (surgery/RT) | 0.62 | 0.14–2.43 | 0.50 | 1.50 | 0.37–5.72 | 0.56 |
| Model 2-SUVpeak | ||||||
| SUVpeak (≥19/<19) | 2.73 | 0.83–8.00 | 0.09 | 1.49 | 0.33–5.04 | 0.57 |
| T category (T4/T1-3) | 4.18 | 0.97–16.40 | 0.09 | 2.19 | 0.49–9.00 | 0.29 |
| Treatment group (surgery/RT) | 0.52 | 0.12–2.02 | 0.35 | 1.38 | 0.34–5.20 | 0.64 |
| Model 3-MTV | ||||||
| MTV (≥12/<12) | 3.29 | 0.48–29.91 | 0.22 | 2.68 | 0.36–27.14 | 0.34 |
| T category (T4/T1-3) | 3.04 | 0.51–12.86 | 0.20 | 1.38 | 0.15–7.71 | 0.75 |
| Treatment group (surgery/RT) | 0.37 | 0.05–1.60 | 0.20 | 1.15 | 0.23–4.58 | 0.85 |
| Model 4-TLG | ||||||
| TLG (≥42/<42) | 4.00 | 1.11–18.74 | <0.04 | 6.61 | 1.59–44.67 | <0.01 |
| T category (T4/T1-3) | 2.16 | 0.51–8.54 | 0.28 | 1.04 | 0.23–4.46 | 0.64 |
| Treatment group (surgery/RT) | 0.59 | 0.15–2.14 | 0.43 | 1.57 | 0.39–5.84 | 0.51 |
a
Cox proportional hazard model. OS, overall survival; DMFS, distant metastasis-free survival; HR, hazard ratio; CI, confidence interval; SUV, standardized uptake value; MTV, metabolic tumor volume; TLG, total lesion glycolysis; RT, radiotherapy.