Table II.
Association between HIF-1α expression and the clinicopathological characteristics.
| HIF-1α expression | |||
|---|---|---|---|
| Characteristic | High | Low | P-value |
| Mean age (years) | 70.8 | 70.0 | 0.56 |
| Gender (n) | |||
| Male | 39 | 99 | 0.64 |
| Female | 19 | 59 | |
| Smoking status (n) | |||
| Non-smoker | 12 | 41 | 0.54 |
| Smoker | 46 | 117 | |
| Pathological tumor stage (n) | |||
| I | 38 | 109 | 0.75 |
| ≥II | 20 | 49 | |
| Histological tumor type (n) | |||
| Squamous | 27 | 27 | <0.01 |
| Non-squamous | 31 | 131 | |
| Lymphatic invasion (n) | |||
| + | 16 | 22 | 0.03 |
| − | 42 | 136 | |
| Venous invasion (n) | |||
| + | 35 | 73 | 0.09 |
| − | 23 | 85 | |
| Mean tumor size (mm) | 33.4 | 30.2 | 0.18 |
| Mean GGO ratio (%) | 8.9 | 19.0 | 0.02 |
| SUVmax (n) | |||
| ≥5 | 30 | 50 | <0.01 |
| <5 | 17 | 79 | |
| Tumor differentiation (n) | |||
| G1 | 9 | 49 | 0.03 |
| ≥G2 | 47 | 101 | |
HIF-1α, hypoxia-inducible factor-1α; GGO, ground glass opacity; SUVmax, maximum standardized uptake value.