Figure 4.

Cell clusters of multiple type 2 alveolar epithelial cells exist in Bax-deficient Ku70 KO mice. Lung sections of wt, ku70^−/−, and ku70^−/−bax^−/− mice were stained by pro-SPC antibody detecting type 2 alveolar epithelial (AT2) cells. AT2 cell does not form multiple cell clusters in wt and ku70^−/− mice, but AT2 cell clusters were often detected in ku70^−/−bax^−/− mice. Experiments were performed as previously reported in Ngo et al.³² (A color version of this figure is available in the online journal.)