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. 2016 May 2;241(10):1138–1148. doi: 10.1177/1535370216647126

Figure 4.

Figure 4

Schematics and scanning electron microscope images of in vitro PolySTAT-induced fibrin clots. Fibrin clots showed binding specificity for PolySTAT over PBS and scrambled nonbinding polymer PolySCRAM. PolySTAT induced clot formation through fibrin crosslinking in a manner reminiscent of natural factor XIIIa-induced crosslinking. Scale bars = 250 nm. From (Chan LW, Wang X, Wei H, Pozzo LD, White NJ, Pun SH. A synthetic fibrin cross-linking polymer for modulating clot properties and inducing hemostasis. Sci Transl Med 2015;7:277ra29.). Reprinted with permission from AAAS. (A color version of this figure is available in the online journal.)