Figure 1.
(a) Model-estimated hazard ratio for major depressive episode onset, in the presence or absence of several types of major severity stressful life events (SLEs) within the previous two months, separated by 5-HTTLPR genotype. Hazard ratios for major non-interpersonal and major interpersonal SLEs are derived from the combined dichotomous SLE model for these variables reported in Table 3. SE(β)s and 95% CIs for each term in the models are presented in Table 3. Raw hazard for major depressive episode onset (number of onsets divided by number of person months available under a given set of conditions) by severity of chronic family stress and 5-HTTLPR genotype.