Effect of naringin on inflammatory factors in AS mouse model. The protective effect of naringin on the activity (A) NF-κB p65 unit, (B) TNF-α, (C) IL-1β and (D) IL-6 values in the AS mouse model. ##P<0.01 vs. control group; *P<0.05 vs. AS group; **P<0.01 vs. AS group. NF-κB p65, nuclear factor-κB p65; AS, ankylosing spondylitis group; Nar (20), naringin (20 mg/kg)-treated; Nar (40), naringin (40 mg/kg)-treated; Nar (80), naringin (80 mg/kg)-treated; One way analysis of variance was performed for the statistical analysis of data, the Student's t-test was used to analyze statistical significance. TNF-α, tumor necrosis factor-α; IL, interleukin.