Effect of naringin on oxidative stress markers in AS mouse model. The protective effect of naringin on the concentrations of (A) MDA, (B) SOD, (C) CAT and (D) GSH-PX in the AS mouse model. ##P<0.01 vs. control group; *P<0.05 vs. AS group; **P<0.01 vs. AS group. MDA, malondialdehyde; AS, ankylosing spondylitis group; Nar (20), naringin (20 mg/kg)-treated; Nar (40), naringin (40 mg/kg)-treated; Nar (80), naringin (80 mg/kg)-treated; One way analysis of variance was performed for the statistical analysis of data, the Student's t-test was used to analyze statistical significance. SOD, superoxide dismutase; CAT, catalase; GSH-PX, glutathione peroxidase.