Table 2.

Linear mixed model analyses for long-term disability (total score WHODAS-II)^a

	Disability
	Univariable		Model 1		Model 2		Model 3
	ß (SE)	p	ß (SE)	p	ß (SE)	p	ß (SE)	p
Baseline psychiatric status
Healthy controls	Ref		Ref		Ref		Ref
SAD	15.28 (1.55)	<.001	14.26 (1.74)	<.001	5.09 (1.42)	<.001	4.38 (1.55)	<.001
SAD x time	-6.48 (0.61)	<.001	-6.40 (0.61)	<.001	-2.52 (0.57)	.01	-2.56 (0.57)	.01
PDA	9.31 (2.09)	<.001	9.54 (2.24)	<.001	-0.46 (1.88)	.65	-0.65 (1.98)	.52
PDA x time	-4.18 (0.85)	<.001	-4.04 (0.85)	<.001	-0.07 (0.77)	.94	-0.11 (0.77)	.92
PD	5.96 (2.15)	<.001	6.40 (2.29)	<.001	0.46 (1.84)	.65	0.23 (1.94)	.82
PD x time	-1.43 (0.88)	.15	-1.29 (0.88)	.20	-0.07 (0.77)	.95	-0.11 (0.77)	.92
GAD	13.01 (1.93)	<.001	13.19 (2.07)	<.001	6.62 (1.68)	<.001	6.07 (1.77)	<.001
GAD x time	-5.80 (0.79)	<.001	-5.58 (0.80)	<.001	-3.52 (0.70)	<.001	-3.55 (0.70)	<.001
Multiple AD	20.93 (1.57)	<.001	18.21 (1.58)	<.001	3.58 (1.46)	<.001	3.00 (1.58)	.003
Multiple AD x time	-7.61 (0.54)	<.001	-7.54 (0.54)	<.001	-1.31 (0.58)	.19	-1.36 (0.58)	.18
Psychiatric course trajectory
Healthy controls	Ref		Ref				Ref
Remission	10.30 (0.82)	<.001	-3.12 (1.12)	.002			0.63 (0.84)	.53
Recurrence	7.82 (1.66)	<.001	-0.01 (1.70)	.99			0.42 (1.23)	.67
Chronic course	14.65 (1.32)	<.001	3.65 (1.48)	<.001			0.94 (1.08)	.35
Symptom dimensions
Anxiety arousal	24.28 (0.04)	<.001			12.49 (0.06)	<.001	12.51 (0.06)	<.001
Anxiety arousal x time	1.49 (0.02)	.14			0.90 (0.03)	.37	0.86 (0.03)	.39
Avoidance behaviour	23.28 (0.02)	<.001			10.58 (0.03)	<.001	10.57 (0.03)	<.001
Avoidance behaviour x time	-1.40 (0.01)	.16			0.17 (0.01)	.87	0.14 (0.01)	.89

^aAnalyses corrected for covariates age, sex, education, partner status, number of somatic illnesses and comorbid depression

Model 1: baseline psychiatric status and course trajectories; Model 2: baseline psychiatric status and symptom dimensions; Model 3: final model