Figure 1.
SNF2H is highly expressed in HCC. (A) Western blot assays showed that SNF2H expression in HCC was increased compared with the corresponding paratumoral tissues. (B) Reverse transcription-quantitative polymerase chain reaction analysis of SNF2H expression in HCC and corresponding paratumoral tissues. The relative expression of SNF2H mRNA in HCC tissue samples was increased compared with the paired paratumoral tissues. (C) SNF2H protein levels in the normal liver cell were decreased compared with several HCC cell lines. Western blotting showed that the HCC cell lines Huh7 and MHCC97H express more SNF2H than the normal liver L02 cell lines. (D) The SNF2H mRNA level in the HCC cell lines was increased compared with the mRNA level in the L02 cell line. Significant differences were determined by Student's t-test. *P<0.05; **P<0.01; ***P<0.001. SNF2H, SWItch/sucrose nonfermentable catalytic subunit SNF2; HCC, hepatocellular carcinoma; mRNA, messenger RNA; pT, paratumoral; T, tumor.