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. 2016 Jun 7;12(2):1329–1336. doi: 10.3892/ol.2016.4681

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — SNF2H promotes HCC cell proliferation in vitro. (A) SNF2H expression in HCC cells infected with lentivirus. The left panel shows overexpression of SNF2H in BEL-7402 cells. The right panel shows knockdown of SNF2H expression in Huh7 cells. (B) The Cell Counting Kit-8 assay revealed that SNF2H overexpression significantly improved the cell growth rate (left panel). Knockdown of SNF2H expression in Huh7 cells significantly reduced the cell growth rate. The mean ± SD from three independent experiments is presented. (C) SNF2H promotes HCC cell colony formation. The left panel shows that overexpression of SNF2H expression promoted cell colony-forming capacity in BEL-7402 cells. The right panel shows that knockdown of SNF2H expression inhibited colony formation in Huh7 cells. The mean ± SD from three independent experiments is presented. Significant differences were determined by Student's t-test. *P<0.05; **P<0.01; ***P<0.001. SNF2H, SWItch/sucrose nonfermentable catalytic subunit SNF2; HCC, hepatocellular carcinoma; SD, standard deviation; SCR, scrambled small interfering RNA precursor; OD, optical density.