Table II.

Effect of myrrh on histopathological changes in the colonic tissues of rats with AA-induced ulcerative colitis.

Group	Inflammatory cell infiltration	Surface ulceration and necrosis	Edema and hyperemia	Goblet cell hyperplasia	Total score
Control	0	0	0	0	0
AA	4	4	4	3	15
Myrrh (mg/kg/day)
125	3	3	2	1	9
250	2	2	2	2	8
500	2	0	1	0	3
MES (300 mg/kg/day)	1	1	1	0	3

Sections were scored for inflammatory cell infiltration, surface ulceration and necrosis, edema and hyperemia and goblet cell hyperplasia, as follows: 1, <25% damage or active changes; 2, <50% damage or active changes; 3, <75% damage or active changes; and 4, >75% damage or active changes. A total score of <4 indicated minimal inflammatory changes, a score of 4–8 indicated mild inflammatory changes, a score of 9–12 indicated moderate inflammatory changes and a score of 13–16 indicated severe inflammatory changes. AA, acetic acid; MES, mesalazine.