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. 2016 Jul 19;17:85. doi: 10.1186/s12931-016-0407-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Panel a: Density of particles as a function of the diameter of silver nanoparticles measured during each of the experimental conditions for each rat strain. BN-LD: Brown Norway rats exposed to low dose; BN-HD: Brown Norway rats exposed to high dose; SD-LD: Sprague–Dawley rats exposed to low dose; SD-HD: Sprague–Dawley rats exposed to high-dose. Panel b: Representative high resolution transmission electron microscopy (TEM) images of aerosol particles delivered to the exposure manifold at 12,000X magnification (scale bar 200 nm) (Panel B a) and 800,000X magnification (scale bar 2 nm) (Panel B b)