Table 1.
Characterisation of spark generated silver nanoparticles and lung burden on each of the exposure conditions for the two rat strains
| Sprague–Dawley rats | Brown-Norway rats | |||||
|---|---|---|---|---|---|---|
| Control | Low dose | High dose | Control | Low dose | High dose | |
| Count Median Diameter (nm) | - | 13.4 ± 1.0 | 14.1 ± 2.3 | - | 15.9 ± 0.8 | 15.7 ± 2.8 |
| Geometric Standard Deviation | - | 1.60 ± 0.03 | 1.58 ± 0.06 | - | 1.58 ± 0.02 | 1.56 ± 0.06 |
| Concentration /cm3 | <1 | (4.50 ± 0.21) x 107 | (4.55 ± 0.70) x 107 | <1 | (3.89 ± 0.18) x 107 | (3.68 ± 0.48) x 107 |
| Mass concentration (μg/m3) | - | 801 ± 33 | 670 ± 49 | - | 791 ± 32 | 617 ± 25 |
| Exposure duration (mins) | 720 | 180 | 720 | 720 | 180 | 720 |
| Lung burden (μg) | 0 | 8 | 28 | 0 | 8 | 26 |
| Alveolar dose (μg) | 0 | 6 | 19 | 0 | 6 | 18 |