Table 2.

Overview of clinical parameters and relative serum expression of MMP7, MMP10 and MMP12

Patient Characteristics	N	Median relative serum expression
		MMP7	p	MMP10	P	MMP12	p
Gender			0.049		0.138		0.004
Male	51	1.21		1.22		1.19
Female	24	0.97		0.95		0.88
Age at operation			0.013		0.003		0.253
<median = 64 years	37	0.95		0.95		1.16
≥ median = 64 years	38	1.2		1.36		1.03
T-Stage			0.582		0.957		0.481
T1	2	0.86		0.9		0.42
T2	8	0.92		1.13		1.11
T3	53	1.08		1.13		1.07
T4	13	1.24		1.22		1.19
N-Stage			0.806		0.074		0.301
Node negative	29	1.06		1.22		1.0
Node positive	46	1.16		0.99		1.14
M-Stage			0.244		0.603		0.087
M0	55	1.06		1.13		1.0
M1	23	1.26		1.13		1.19
L-Stage			0.629		0.085		0.593
L0	61	1.06		1.18		1.06
L1	14	1.25		0.81		1.14
V-Stage			0.067		0.321		0.018
V0	69	1.06		1.13		1.06
V1	6	2.41		1.86		1.32
Micro satellite stage			0.053		0.845		0.844
MSS	5	0.68		0.76		0.47
MSI	2	1.16		0.95		1.01
Tumor site			<0.001*		0.76		0.758
Coecum	17	0.98		1.22		1.16
Colon ascendens	14	1.11		0.88		0.78
Right colon flexure	6	1.28		1.32		1.13
Colon transversum	3	1.37		0.86		1.0
Colon descendens	5	2.12		2.16		1.29
Colon sigmoideum	30	0.96		0.99		1.14

*In ANOVA p < 0.001, the post-hoc Tukey’s test showed a significant difference between colon descendens and coecum, colon ascendens and right colon flexure (p < 0.001; p < 0.001; p = 0.007, respectively)