Table 1.
Wild type and mutant S. pneumoniae strains used
| Strain | Capsule serotype | Description |
|---|---|---|
| B201.73 | 19F | Wild types (clinical isolates) [12] |
| 103.57 | 23F | |
| B101.77 | 14 | |
| 307.14 | 18C | |
| 109.74 | 9V | |
| 207.31 | 15 | |
| 106.66 | 6B | |
| 208.41 | 7F | |
| P21 | 3 | Wild type [13] |
| 106.66 Janus | nonencapsulated | Capsule operon replaced by a Janus cassette [12] |
| 106.66cps106.66 | 6B | Capsule switch mutants [12] |
| 106.66cpsB201.73 | 19F | |
| 106.66cps103.57 | 23F | |
| 106.66cpsB101.77 | 14 | |
| 106.66cps307.14 | 18C | |
| 106.66cps109.74 | 9V | |
| 106.66cps207.31 | 15 | |
| 106.66cps208.41 | 7F | |
| B103.21 | 1 | Wild type, non-haemolytic (current study) |
| 211.25 | 1 | Wild type, poorly haemolytic (current study) |
| 207.06 | 1 | Wild type, haemolytic (current study) |
| 202.67 | 1 | Wild type, non-haemolytic (current study) |
| D39 | 2 | Wild type [11] |
| D39Δply | 2 | Mutant lacking pneumolysin [11] |
| D39Δcps | nonencapsulated | Mutant lacking capsule [11] |
| D39ΔplyΔcps | nonencapsulated | Mutant lacking pneumolysin and capsule [11] |