Table 2.
Blood data
| Variable | Group | PRE | Week 4 | Week 8 | POST | p |
|---|---|---|---|---|---|---|
| Irisin (μg/mL) | PLA | 1.30 ± 0.39 | 1.65 ± 0.65 | 0.89 ± 0.36 | 0.79 ± 0.38 | 0.06 |
| TRT | 1.20 ± 0.35 | 1.19 ± 0.39 | 1.07 ± 0.35a | 0.97 ± 0.50 | ||
| IL-6 (pg/mL) | PLA | 1.57 ± 2.62 | 1.39 ± 0.57 | 1.20 ± 0.67 | 1.04 ± 0.56 | 0.52 |
| TRT | 2.29 ± 3.65 | 1.55 ± 1.56 | 1.42 ± 0.83 | 0.95 ± 0.58 | ||
| IL-15 (pg/mL) | PLA | 2.21 ± 0.49 | 2.8 ± 0.64 | 2.68 ± 0.66 | 3.36 ± 0.94 | 0.61 |
| TRT | 2.15 ± 0.48 | 2.54 ± 0.66 | 2.41 ± 0.69 | 3.11 ± 0.83 | ||
| FGF-21 (pg/mL) | PLA | 80.1 ± 14.9 | 119.0 ± 34.1 | 106.5 ± 7.51 | 81.8 ± 4.6 | 0.41 |
| TRT | 75.5 ± 7.5 | 116.8 ± 23.9 | 104.2 ± 8.5 | 105.0 ± 76.3 | ||
| Myonectin (ng/mL) | PLA | 0.26 ± 0.14 | 0.21 ± 0.08 | 0.20 ± 0.13 | 0.36 ± 0.46 | 0.58 |
| TRT | 0.81 ± 1.52 | 0.70 ± 1.34 | 0.64 ± 1.2 | 0.99 ± 2.05 | ||
| Cortisol (ng/mL) | PLA | 39.0 ± 20.5 | 64.0 ± 27.5 | 70.7 ± 29.5 | 53.1 ± 19.1 | 0.11 |
| TRT | 47.0 ± 22.0 | 43.4 ± 25.8 | 63.3 ± 27.6 | 53.3 ± 15.1 | ||
| CRP (ng/mL) | PLA | 18.1 ± 38.8 | 11.8 ± 13.0 | 8.1 ± 9.6 | 9.3 ± 8.9 | 0.43 |
| TRT | 11.0 ± 14.2 | 17.4 ± 25.2 | 10.0 ± 14.4 | 6.0 ± 7.5 | ||
| GDF-11 (ng/mL) | PLA | 0.99 ± 0.58 | 1.11 ± 0.83 | 0.49 ± 0.40 | 0.66 ± 0.57 | 0.19 |
| TRT | 0.61 ± 0.48 | 0.55 ± 0.53 | 0.21 ± 0.29 | 0.37 ± 0.35 |
Data are presented as mean ± standard deviation. The p-value is derived from an ANOVA and representative of an interaction effect for group by time. A significant difference from PLA is aif different from week 4