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. 2016 Jul 19;15:99. doi: 10.1186/s12933-016-0416-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Diastolic function (ΔdP/dt_min) in supply ischemia protocol. Mean ± SEM. There were no statistically significant differences between groups at BO1. At BL2, dP/dt_min for GLP-1 was significantly improved compared to control (p < 0.01) and numerically better than glibenclamide alone (p = 0.07). The difference between GLP-1 vs. control was maintained at BO2 (p = 0.01). At BL2, dP/dt_min for GLP-1 + glibenclamide was again significantly improved compared to control (p < 0.01), and numerically better than glibenclamide alone (p = 0.15). These differences persisted for BO2 (p < 0.01 and 0.06 respectively). There was no statistically significant difference between GLP-1 treated groups, nor any difference between the control and glibenclamide only groups, at any timepoint