Table 6.
Diagnosis of intermediate- and/or high-risk endometrial cancers by preoperative assessment (MRI and endometrial sample) (n = 91)
| Endometrial sample | MRI | Combination (MRI and histology) | |||
|---|---|---|---|---|---|
| Type 2 | Grade 3 | FIGO Stage > IA | High risk | Intermediate and high risk | |
| Sensitivity (%) [95 % CI] | 63.6 [35.4–84.8] | 30.0 [10.8–60.3] | 78.3 [64.4–87.7] | 47.7 [33.8–62.1] | 70.0 [58.0–80.8] |
| Specificity (%) [95 % CI] | 95.0 [87.8–98.0] | 98.4 [91.7–99.7] | 88.9 [76.5–95.2] | 93.6 [82.8–97.8] | 81.8 [65.6–91.4] |
| PPV (%) [95 % CI] | 63.6 [35.4–84.8] | 75.0 [30.1–95.4] | 87.8 [74.5–94.7] | 87.5 [69.0–95.7] | 87.2 [74.8–94.0] |
| NPV (%) [95 % CI] | 95.0 [87.8–98.0] | 90.0 [80.8–95.1] | 80.0 [67.0–88.8] | 65.7 [53.7–75.9] | 61.4 [46.6–74.3] |
| +LR [95 % CI] | 12.7 [4.4–36.5] | 19.2 [2.2–166.9] | 7.0 [3.0–16.3] | 7.5 [2.4–23.3] | 3.8 [1.8–8.2] |
| -LR [95 % CI] | 0.4 [0.1–0.8] | 0.7 [0.4–1.1] | 0.2 [0.1–0.4] | 0.6 [0.4–0.7] | 0.3 [0.2–0.5] |
PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, −LR negative likelihood ratio