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. 2016 Jun 15;5(2):289–294. doi: 10.3892/mco.2016.936

Table II.

Recurrence patterns and time to recurrence in patients with high-grade glioma.

Recurrence pattern Patients, n (%) Time to recurrence (months), median (range) Recurrence rate at 1 year (%) Recurrence rate at 2 years (%)
Central recurrence 34 (63.0) 11 (2–30) 56   94
In-field recurrence 8 (14.8)   9 (3–11) 100 100
Marginal recurrence 2 (3.7) 30 (2–58) 50   50
Distant recurrence 2 (3.7) 19 (2–35) 50   50
CSF-d 11 (20.4) 10 (5–58) 55   82

The time to recurrence was calculated from the date of pathological diagnosis. Of the 11 patients who developed CSF-d, 2 developed central recurrence and 1 simultaneously developed marginal recurrence. CSF-d, cerebrospinal fluid dissemination.